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PAMAM-cRGD mediating efficient siRNA delivery to spermatogonial stem cells

BACKGROUND: Spermatogonial stem cells (SSCs) are the cornerstone of sperm production and thus perpetual male fertility. In clinics, transplantation of patient’s own SSCs into testes is a promising technique to restore fertility when male germ cells have been depleted by gonadotoxic therapies. Auto-t...

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Detalles Bibliográficos
Autores principales: Li, Tianjiao, Chen, Qiwen, Zheng, Yi, Zhang, Pengfei, Chen, Xiaoxu, Lu, Junna, Lv, Yinghua, Sun, Shiguo, Zeng, Wenxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921429/
https://www.ncbi.nlm.nih.gov/pubmed/31852526
http://dx.doi.org/10.1186/s13287-019-1506-4