Cargando…

PAMAM-cRGD mediating efficient siRNA delivery to spermatogonial stem cells

BACKGROUND: Spermatogonial stem cells (SSCs) are the cornerstone of sperm production and thus perpetual male fertility. In clinics, transplantation of patient’s own SSCs into testes is a promising technique to restore fertility when male germ cells have been depleted by gonadotoxic therapies. Auto-t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Tianjiao, Chen, Qiwen, Zheng, Yi, Zhang, Pengfei, Chen, Xiaoxu, Lu, Junna, Lv, Yinghua, Sun, Shiguo, Zeng, Wenxian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921429/ https://www.ncbi.nlm.nih.gov/pubmed/31852526 http://dx.doi.org/10.1186/s13287-019-1506-4

Ejemplares similares

Enhanced Intercellular Delivery of cRGD–siRNA Conjugates by an Additional Oligospermine Modification
por: Nakamoto, Kosuke, et al.
Publicado: (2018)

Systemic Administration of siRNA via cRGD-containing Peptide
por: Huang, Yuanyu, et al.
Publicado: (2015)

Tumor-targeted in vivo gene silencing via systemic delivery of cRGD-conjugated siRNA
por: Liu, Xiaoxia, et al.
Publicado: (2014)

Protective effect of Gelofusine against cRGD-siRNA-induced nephrotoxicity in mice
por: Liao, Wenjie, et al.
Publicado: (2018)

cRGD peptide-conjugated polyethylenimine-based lipid nanoparticle for intracellular delivery of siRNA in hepatocarcinoma therapy
por: Yang, Shuang, et al.
Publicado: (2021)

Reductive nanocomplex encapsulation of cRGD-siRNA conjugates for enhanced targeting to cancer cells
por: Zhou, Zhaoxiu, et al.
Publicado: (2017)

Feasibility of cRGD conjugation at 5′-antisense strand of siRNA by phosphodiester linkage extension
por: Zhou, Xinyang, et al.
Publicado: (2021)

Macrophage membrane- and cRGD-functionalized thermosensitive liposomes combined with CPP to realize precise siRNA delivery into tumor cells
por: Nai, Jingxue, et al.
Publicado: (2021)

Acetylation of PAMAM dendrimers for cellular delivery of siRNA
por: Waite, Carolyn L, et al.
Publicado: (2009)

Gelofusine Attenuates Tubulointerstitial Injury Induced by cRGD-Conjugated siRNA by Regulating the TLR3 Signaling Pathway
por: Cen, Bohong, et al.
Publicado: (2018)

A tumor-targeting cRGD-EGFR siRNA conjugate and its anti-tumor effect on glioblastoma in vitro and in vivo
por: He, Shuai, et al.
Publicado: (2017)

Enhanced Specificity and Drug Delivery in Tumors by cRGD - Anchoring Thermosensitive Liposomes
por: Dicheva, Bilyana M., et al.
Publicado: (2015)

Multifunctional Triblock Nanocarrier (PAMAM-PEG-PLL) for the Efficient Intracellular siRNA Delivery and Gene Silencing
por: Patil, Mahesh L., et al.
Publicado: (2011)

Gold Nanorods Conjugated with Doxorubicin and cRGD for Combined Anticancer Drug Delivery and PET Imaging
por: Xiao, Yuling, et al.
Publicado: (2012)

Functional cRGD-Conjugated Polymer Prodrug for Targeted Drug Delivery to Liver Cancer Cells
por: Zhou, Ru, et al.
Publicado: (2022)

Alendronate/cRGD-Decorated Ultrafine Hyaluronate Dot Targeting Bone Metastasis
por: Lee, Eunsol, et al.
Publicado: (2020)

cRGD Urokinase Liposomes for Thrombolysis in Rat Model of Acute Pulmonary Microthromboembolism
por: Liang, Chunting, et al.
Publicado: (2022)

PAMAM versus PEI complexation for siRNA delivery: interaction with model lipid membranes and cellular uptake
por: Chang, Patrick K. C., et al.
Publicado: (2022)

Non-Cationic RGD-Containing Protein Nanocarrier for Tumor-Targeted siRNA Delivery
por: Yu, Xiaolin, et al.
Publicado: (2021)

An RGD-Modified MRI-Visible Polymeric Vector for Targeted siRNA Delivery to Hepatocellular Carcinoma in Nude Mice
por: Wu, Chun, et al.
Publicado: (2013)

Novel PAMAM-PEG-Peptide Conjugates for siRNA Delivery Targeted to the Transferrin and Epidermal Growth Factor Receptors
por: Urbiola, Koldo, et al.
Publicado: (2018)

Fabrication of cRGD-modified reduction-sensitive nanocapsule via Pickering emulsion route to facilitate tumor-targeted delivery
por: Shang, Xingxing, et al.
Publicado: (2019)

Preparation of DSPE-PEG-cRGD Modified Cationic Liposomes for Delivery of OC-2 shRNA and The Antitumor Effects on Breast Cancer
por: Liu, Chunyan, et al.
Publicado: (2022)

Targeted Diagnosis, Therapeutic Monitoring, and Assessment of Atherosclerosis Based on Mesoporous Silica Nanoparticles Coated with cRGD-Platelets
por: Zhang, Wei, et al.
Publicado: (2022)

Iodine-125-labeled cRGD-gold nanoparticles as tumor-targeted radiosensitizer and imaging agent
por: Su, Ning, et al.
Publicado: (2015)

Interface Immobilization Chemistry of cRGD-based Peptides Regulates Integrin Mediated Cell Adhesion
por: Pallarola, Diego, et al.
Publicado: (2014)

Endothelial Cell Targeting by cRGD-Functionalized Polymeric Nanoparticles under Static and Flow Conditions
por: Martínez-Jothar, Lucía, et al.
Publicado: (2020)

Targeting Ultrasmall Gold Nanoparticles with cRGD Peptide Increases the Uptake and Efficacy of Cytotoxic Payload
por: Perrins, Richard D., et al.
Publicado: (2022)

Scanning Tunneling Microscopy Study of Lipoic Acid, Mannose, and cRGD@AuNPs Conjugates
por: Rodríguez-Galván, Andrés, et al.
Publicado: (2023)

Co-Delivery of Gemcitabine and Paclitaxel in cRGD-Modified Long Circulating Nanoparticles with Asymmetric Lipid Layers for Breast Cancer Treatment
por: Zhang, Jing, et al.
Publicado: (2018)

Effects of diagnostic ultrasound with cRGD-microbubbles on simultaneous detection and treatment of atherosclerotic plaque in ApoE(−/−) mice
por: Guo, Shengcun, et al.
Publicado: (2022)

Enhanced tumor targeting of cRGD peptide-conjugated albumin nanoparticles in the BxPC-3 cell line
por: Yu, Xinzhe, et al.
Publicado: (2016)

Evolution from Covalent to Self-Assembled PAMAM-Based Dendrimers as Nanovectors for siRNA Delivery in Cancer by Coupled In Silico-Experimental Studies. Part I: Covalent siRNA Nanocarriers
por: Marson, Domenico, et al.
Publicado: (2019)

Ultrasound molecular imaging with cRGD-PLGA-PFOB nanoparticles for liver fibrosis staging in a rat model
por: Xuan, Jiqing, et al.
Publicado: (2017)

Treatment of acute lung inflammation by pulmonary delivery of anti-TNF-α siRNA with PAMAM dendrimers in a murine model
por: Bohr, Adam, et al.
Publicado: (2020)

Theranostic cRGD-BioShuttle Constructs Containing Temozolomide- and Cy7 For NIR-Imaging and Therapy
por: Wiessler, Manfred, et al.
Publicado: (2011)

Novel RGD-lipid conjugate-modified liposomes for enhancing siRNA delivery in human retinal pigment epithelial cells
por: Chen, Cheng-Wei, et al.
Publicado: (2011)

Evolution from Covalent to Self-Assembled PAMAM-Based Dendrimers as Nanovectors for siRNA Delivery in Cancer by Coupled in Silico-Experimental Studies. Part II: Self-Assembled siRNA Nanocarriers
por: Laurini, Erik, et al.
Publicado: (2019)

cRGD-Conjugated GdIO Nanoclusters for the Theranostics of Pancreatic Cancer through the Combination of T(1)–T(2) Dual-Modal MRI and DTX Delivery
por: Wang, Shengchao, et al.
Publicado: (2023)

The Histone Methyltransferase SETDB1 Modulates Survival of Spermatogonial Stem/Progenitor Cells Through NADPH Oxidase
por: Li, Xueliang, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_b8ala769nln8l4qkk19n16p0m8