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Mycobacterium tuberculosis LipE Has a Lipase/Esterase Activity and Is Important for Intracellular Growth and In Vivo Infection

Mycobacterium tuberculosis Rv3775 (LipE) was annotated as a putative lipase. However, its lipase activity has never been characterized, and its precise role in tuberculosis (TB) pathogenesis has not been thoroughly studied to date. We overexpressed and purified the recombinant LipE (rLipE) protein a...

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Detalles Bibliográficos
Autores principales: Yang, Dong, Li, Shaoji, Stabenow, Jennifer, Zalduondo, Lillian, Kong, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921666/
https://www.ncbi.nlm.nih.gov/pubmed/31636137
http://dx.doi.org/10.1128/IAI.00750-19