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Algorithms for efficiently collapsing reads with Unique Molecular Identifiers

BACKGROUND: Unique Molecular Identifiers (UMI) are used in many experiments to find and remove PCR duplicates. There are many tools for solving the problem of deduplicating reads based on their finding reads with the same alignment coordinates and UMIs. However, many tools either cannot handle subst...

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Detalles Bibliográficos
Autor principal: Liu, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921982/
https://www.ncbi.nlm.nih.gov/pubmed/31871845
http://dx.doi.org/10.7717/peerj.8275