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Genetic Determinants of Lipids and Cardiovascular Disease Outcomes: A Wide-Angled Mendelian Randomization Investigation

Evidence from randomized trials has shown that therapies that lower LDL (low-density lipoprotein)-cholesterol and triglycerides reduce coronary artery disease (CAD) risk. However, there is still uncertainty about their effects on other cardiovascular outcomes. We therefore performed a systematic inv...

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Detalles Bibliográficos
Autores principales: Allara, Elias, Morani, Gabriele, Carter, Paul, Gkatzionis, Apostolos, Zuber, Verena, Foley, Christopher N., Rees, Jessica M.B., Mason, Amy M., Bell, Steven, Gill, Dipender, Lindström, Sara, Butterworth, Adam S., Di Angelantonio, Emanuele, Peters, James, Burgess, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6922071/
https://www.ncbi.nlm.nih.gov/pubmed/31756303
http://dx.doi.org/10.1161/CIRCGEN.119.002711