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Childhood immune imprinting to influenza A shapes birth year-specific risk during seasonal H1N1 and H3N2 epidemics

Across decades of co-circulation in humans, influenza A subtypes H1N1 and H3N2 have caused seasonal epidemics characterized by different age distributions of cases and mortality. H3N2 causes the majority of severe, clinically attended cases in high-risk elderly cohorts, and the majority of overall d...

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Detalles Bibliográficos
Autores principales: Gostic, Katelyn M., Bridge, Rebecca, Brady, Shane, Viboud, Cécile, Worobey, Michael, Lloyd-Smith, James O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6922319/
https://www.ncbi.nlm.nih.gov/pubmed/31856206
http://dx.doi.org/10.1371/journal.ppat.1008109