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High throughput, efficacious gene editing & genome surveillance in Chinese hamster ovary cells

Chinese hamster ovary (CHO) cells are a common tool utilized in bioproduction and directed genome engineering of CHO cells is of great interest to enhance recombinant cell lines. Until recently, this focus has been challenged by a lack of efficacious, high throughput, and low-cost gene editing modal...

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Detalles Bibliográficos
Autores principales: Huhn, S. C., Ou, Y., Kumar, A., Liu, R., Du, Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6922373/
https://www.ncbi.nlm.nih.gov/pubmed/31856197
http://dx.doi.org/10.1371/journal.pone.0218653