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Helminth-induced Th2 cell dysfunction is distinct from exhaustion and is maintained in the absence of antigen

T cell-intrinsic regulation, such as anergy, adaptive tolerance and exhaustion, is central to immune regulation. In contrast to Type 1 and Type 17 settings, knowledge of the intrinsic fate and function of Th2 cells in chronic Type 2 immune responses is lacking. We previously showed that Th2 cells de...

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Detalles Bibliográficos
Autores principales: Knipper, Johanna A., Ivens, Alasdair, Taylor, Matthew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6922449/
https://www.ncbi.nlm.nih.gov/pubmed/31815932
http://dx.doi.org/10.1371/journal.pntd.0007908