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Helminth-induced Th2 cell dysfunction is distinct from exhaustion and is maintained in the absence of antigen
T cell-intrinsic regulation, such as anergy, adaptive tolerance and exhaustion, is central to immune regulation. In contrast to Type 1 and Type 17 settings, knowledge of the intrinsic fate and function of Th2 cells in chronic Type 2 immune responses is lacking. We previously showed that Th2 cells de...
Autores principales: | Knipper, Johanna A., Ivens, Alasdair, Taylor, Matthew D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6922449/ https://www.ncbi.nlm.nih.gov/pubmed/31815932 http://dx.doi.org/10.1371/journal.pntd.0007908 |
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