A cell-based probabilistic approach unveils the concerted action of miRNAs

Mature microRNAs (miRNAs) regulate most human genes through direct base-pairing with mRNAs. We investigate the underlying principles of miRNA regulation in living cells. To this end, we overexpressed miRNAs in different cell types and measured the mRNA decay rate under a paradigm of a transcriptiona...

Descripción completa

Detalles Bibliográficos
Autores principales: Mahlab-Aviv, Shelly, Linial, Nathan, Linial, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6922470/
https://www.ncbi.nlm.nih.gov/pubmed/31790387
http://dx.doi.org/10.1371/journal.pcbi.1007204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6922470/
https://www.ncbi.nlm.nih.gov/pubmed/31790387
http://dx.doi.org/10.1371/journal.pcbi.1007204

Ejemplares similares