Cargando…

Computational pan-genome mapping and pairwise SNP-distance improve detection of Mycobacterium tuberculosis transmission clusters

Next-generation sequencing based base-by-base distance measures have become an integral complement to epidemiological investigation of infectious disease outbreaks. This study introduces PANPASCO, a computational pan-genome mapping based, pairwise distance method that is highly sensitive to differen...

Descripción completa

Detalles Bibliográficos
Autores principales: Jandrasits, Christine, Kröger, Stefan, Haas, Walter, Renard, Bernhard Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6922483/
https://www.ncbi.nlm.nih.gov/pubmed/31815935
http://dx.doi.org/10.1371/journal.pcbi.1007527