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Tau Propagation as a Diagnostic and Therapeutic Target for Dementia: Potentials and Unanswered Questions
A unique clinical course of Alzheimer’s disease (AD), beginning with memory deficit as the earliest symptom, is well-correlated with a progressive pattern of intracellular aggregates of tau (neurofibrillary tangles), which spread from the medial temporal lobe to other brain areas in a stereotypical...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923174/ https://www.ncbi.nlm.nih.gov/pubmed/31920473 http://dx.doi.org/10.3389/fnins.2019.01274 |