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Docosahexaenoic Acid Consumption Impedes Early Interferon- and Chemokine-Related Gene Expression While Suppressing Silica-Triggered Flaring of Murine Lupus

Exposure of lupus-prone female NZBWF1 mice to respirable crystalline silica (cSiO(2)), a known human autoimmune trigger, initiates loss of tolerance, rapid progression of autoimmunity, and early onset of glomerulonephritis. We have previously demonstrated that dietary supplementation with the ω-3 po...

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Detalles Bibliográficos
Autores principales: Benninghoff, Abby D., Bates, Melissa A., Chauhan, Preeti S., Wierenga, Kathryn A., Gilley, Kristen N., Holian, Andrij, Harkema, Jack R., Pestka, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923248/
https://www.ncbi.nlm.nih.gov/pubmed/31921124
http://dx.doi.org/10.3389/fimmu.2019.02851