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PD-L1 regulates tumorigenesis and autophagy of ovarian cancer by activating mTORC signaling

PD-L1 is a well-known immune co-stimulatory molecule that regulates tumour cell escape from immunity by suppressing the immune response. However, the clinical significance of PD-L1 in the progression of ovarian cancer is unclear. Our study demonstrated that PD-L1 is up-regulated in ovarian tumour ti...

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Detalles Bibliográficos
Autores principales: Gao, Hongmin, Zhang, Juan, Ren, Xiaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923342/
https://www.ncbi.nlm.nih.gov/pubmed/31799599
http://dx.doi.org/10.1042/BSR20191041