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Gal-3 is a potential biomarker for spinal cord injury and Gal-3 deficiency attenuates neuroinflammation through ROS/TXNIP/NLRP3 signaling pathway

Spinal cord injury (SCI) often occurs in young and middle-aged population. The present study aimed to clarify the function of Galectin-3 (Gal-3) in neuroinflammation of SCI. Sprague–Dawley (SD) rat models with SCI were established in vivo. PC12 cell model in vitro was induced by lipopolysaccharide (...

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Detalles Bibliográficos
Autores principales: Ren, Zhouliang, Liang, Weidong, Sheng, Jun, Xun, Chuanhui, Xu, Tao, Cao, Rui, Sheng, Weibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923351/
https://www.ncbi.nlm.nih.gov/pubmed/31763668
http://dx.doi.org/10.1042/BSR20192368