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AT1 and AT2 receptors modulate renal tubular cell necroptosis in angiotensin II-infused renal injury mice

Abnormal renin-angiotensin system (RAS) activation plays a critical role in the initiation and progression of chronic kidney disease (CKD) by directly mediating renal tubular cell apoptosis. Our previous study showed that necroptosis may play a more important role than apoptosis in mediating renal t...

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Detalles Bibliográficos
Autores principales: Zhu, Yongjun, Cui, Hongwang, Lv, Jie, Liang, Haiqin, Zheng, Yanping, Wang, Shanzhi, Wang, Min, Wang, Huanan, Ye, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923374/
https://www.ncbi.nlm.nih.gov/pubmed/31857626
http://dx.doi.org/10.1038/s41598-019-55550-8