Requirement for p62 acetylation in the aggregation of ubiquitylated proteins under nutrient stress

Autophagy receptor p62/SQSTM1 promotes the assembly and removal of ubiquitylated proteins by forming p62 bodies and mediating their encapsulation in autophagosomes. Here we show that under nutrient-deficient conditions, cellular p62 specifically undergoes acetylation, which is required for the forma...

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Detalles Bibliográficos
Autores principales: You, Zhiyuan, Jiang, Wen-Xue, Qin, Ling-Yun, Gong, Zhou, Wan, Wei, Li, Jin, Wang, Yusha, Zhang, Hongtao, Peng, Chao, Zhou, Tianhua, Tang, Chun, Liu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923396/
https://www.ncbi.nlm.nih.gov/pubmed/31857589
http://dx.doi.org/10.1038/s41467-019-13718-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923396/
https://www.ncbi.nlm.nih.gov/pubmed/31857589
http://dx.doi.org/10.1038/s41467-019-13718-w

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