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Requirement for p62 acetylation in the aggregation of ubiquitylated proteins under nutrient stress
Autophagy receptor p62/SQSTM1 promotes the assembly and removal of ubiquitylated proteins by forming p62 bodies and mediating their encapsulation in autophagosomes. Here we show that under nutrient-deficient conditions, cellular p62 specifically undergoes acetylation, which is required for the forma...
Autores principales: | You, Zhiyuan, Jiang, Wen-Xue, Qin, Ling-Yun, Gong, Zhou, Wan, Wei, Li, Jin, Wang, Yusha, Zhang, Hongtao, Peng, Chao, Zhou, Tianhua, Tang, Chun, Liu, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923396/ https://www.ncbi.nlm.nih.gov/pubmed/31857589 http://dx.doi.org/10.1038/s41467-019-13718-w |
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