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TopControl: A Tool to Prioritize Candidate Disease-associated Genes based on Topological Network Features

Putative disease-associated genes are often identified among those genes that are differentially expressed in disease and in normal conditions. This strategy typically yields thousands of genes. Gene prioritizing schemes boost the power of identifying the most promising disease-associated genes amon...

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Detalles Bibliográficos
Autores principales: Nazarieh, Maryam, Helms, Volkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923402/
https://www.ncbi.nlm.nih.gov/pubmed/31857653
http://dx.doi.org/10.1038/s41598-019-55954-6