Helix 8 is the essential structural motif of mechanosensitive GPCRs

G-protein coupled receptors (GPCRs) are versatile cellular sensors for chemical stimuli, but also serve as mechanosensors involved in various (patho)physiological settings like vascular regulation, cardiac hypertrophy and preeclampsia. However, the molecular mechanisms underlying mechanically induce...

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Detalles Bibliográficos
Autores principales: Erdogmus, Serap, Storch, Ursula, Danner, Laura, Becker, Jasmin, Winter, Michaela, Ziegler, Nicole, Wirth, Angela, Offermanns, Stefan, Hoffmann, Carsten, Gudermann, Thomas, Mederos y Schnitzler, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923424/
https://www.ncbi.nlm.nih.gov/pubmed/31857598
http://dx.doi.org/10.1038/s41467-019-13722-0