Multi-functional genome-wide CRISPR system for high throughput genotype–phenotype mapping

Genome-scale engineering is an indispensable tool to understand genome functions due to our limited knowledge of cellular networks. Unfortunately, most existing methods for genome-wide genotype–phenotype mapping are limited to a single mode of genomic alteration, i.e. overexpression, repression, or...

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Detalles Bibliográficos
Autores principales: Lian, Jiazhang, Schultz, Carl, Cao, Mingfeng, HamediRad, Mohammad, Zhao, Huimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923430/
https://www.ncbi.nlm.nih.gov/pubmed/31857575
http://dx.doi.org/10.1038/s41467-019-13621-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923430/
https://www.ncbi.nlm.nih.gov/pubmed/31857575
http://dx.doi.org/10.1038/s41467-019-13621-4

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