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SHBG141–161 Domain-Peptide Stimulates GPRC6A-Mediated Response in Leydig and β-Langerhans cell lines

GPRC6A is acknowledged as a major regulator of energy metabolism and male fertility through the action of undercarboxylated osteocalcin (ucOCN), representing a possible therapeutic target. We recently showed that the sex hormone-binding globulin (SHBG) binds to GPRC6A through the likely involvement...

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Detalles Bibliográficos
Autores principales: De Toni, Luca, Guidolin, Diego, De Filippis, Vincenzo, Peterle, Daniele, Rocca, Maria Santa, Di Nisio, Andrea, De Rocco Ponce, Maurizio, Foresta, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923452/
https://www.ncbi.nlm.nih.gov/pubmed/31857654
http://dx.doi.org/10.1038/s41598-019-55941-x