Fractional Laser-Mediated siRNA Delivery for Mitigating Psoriasis-like Lesions via IL-6 Silencing

The poor permeability of topically applied macromolecules such as small interfering RNA (siRNA) has inhibited the translation to clinical application. In this study, the fractional CO(2) laser-assisted approach was developed to describe siRNA permeation enhancement mediated by the created microchann...

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Detalles Bibliográficos
Autores principales: Lee, Woan-Ruoh, Lin, Yin-Ku, Alalaiwe, Ahmed, Wang, Pei-Wen, Liu, Pei-Yin, Fang, Jia-You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923496/
https://www.ncbi.nlm.nih.gov/pubmed/31855833
http://dx.doi.org/10.1016/j.omtn.2019.11.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923496/
https://www.ncbi.nlm.nih.gov/pubmed/31855833
http://dx.doi.org/10.1016/j.omtn.2019.11.013

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