Machine Learning Enables Accurate Prediction of Asparagine Deamidation Probability and Rate

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The spontaneous conversion of asparagine residues to aspartic acid or iso-aspartic acid, via deamidation, is a major pathway of protein degradation and is often seriously disruptive to biological systems. Deamidation has been shown to negatively affect both in vitro stability and in vivo biological...

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Detalles Bibliográficos
Autores principales: Delmar, Jared A., Wang, Jihong, Choi, Seo Woo, Martins, Jason A., Mikhail, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923510/
https://www.ncbi.nlm.nih.gov/pubmed/31890727
http://dx.doi.org/10.1016/j.omtm.2019.09.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923510/
https://www.ncbi.nlm.nih.gov/pubmed/31890727
http://dx.doi.org/10.1016/j.omtm.2019.09.008

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