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Machine Learning Enables Accurate Prediction of Asparagine Deamidation Probability and Rate
The spontaneous conversion of asparagine residues to aspartic acid or iso-aspartic acid, via deamidation, is a major pathway of protein degradation and is often seriously disruptive to biological systems. Deamidation has been shown to negatively affect both in vitro stability and in vivo biological...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923510/ https://www.ncbi.nlm.nih.gov/pubmed/31890727 http://dx.doi.org/10.1016/j.omtm.2019.09.008 |
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