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Natriuretic peptide receptor C contributes to disproportionate right ventricular hypertrophy in a rodent model of obesity-induced heart failure with preserved ejection fraction with pulmonary hypertension

Heart failure with preserved ejection fraction (HFpEF) currently has no therapies that improve mortality. Right ventricular dysfunction and pulmonary hypertension are common in HFpEF, and thought to be driven by obesity and metabolic syndrome. Thus, we hypothesized that an animal model of obesity-in...

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Detalles Bibliográficos
Autores principales: Agrawal, Vineet, Fortune, Niki, Yu, Sheeline, Fuentes, Julio, Shi, Fubiao, Nichols, David, Gleaves, Linda, Poovey, Emily, Wang, Thomas J., Brittain, Evan L., Collins, Sheila, West, James D., Hemnes, Anna R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923530/
https://www.ncbi.nlm.nih.gov/pubmed/31903184
http://dx.doi.org/10.1177/2045894019895452