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Dysregulation of the Mitochondrial Proteome Occurs in Mice Lacking Adiponectin Receptor 1

Decreased serum adiponectin levels in type 2 diabetes has been linked to the onset of mitochondrial dysfunction in diabetic complications by impairing AMPK-SIRT1-PGC-1α signaling via impaired adiponectin receptor 1 (AdipoR1) signaling. Here, we aimed to characterize the previously undefined role of...

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Detalles Bibliográficos
Autores principales: Pepin, Mark E., Koentges, Christoph, Pfeil, Katharina, Gollmer, Johannes, Kersting, Sophia, Wiese, Sebastian, Hoffmann, Michael M., Odening, Katja E., von zur Mühlen, Constantin, Diehl, Philipp, Stachon, Peter, Wolf, Dennis, Wende, Adam R., Bode, Christoph, Zirlik, Andreas, Bugger, Heiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923683/
https://www.ncbi.nlm.nih.gov/pubmed/31920982
http://dx.doi.org/10.3389/fendo.2019.00872