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Fluoride reactivation-enabled sensitive quantification of tabun adducts on human serum albumin by GC–MS/MS via isotope dilution

Organophosphorus nerve agents inhibit the cholinesterase activity by phosphylation of the active site serine. The resulting phosphylated cholinesterase and adducts on human serum albumin (HSA) are appropriate biomarkers for nerve agents exposure. Several methods have been developed for the detection...

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Detalles Bibliográficos
Autores principales: Li, Xiao-Sen, Wu, Ji-Na, Yan, Long, Xing, Zhong-Fang, Liu, Chang-Cai, Chen, Bo, Yuan, Ling, Yang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Newlands Press Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923783/
https://www.ncbi.nlm.nih.gov/pubmed/31729243
http://dx.doi.org/10.4155/bio-2019-0161