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Fluoride reactivation-enabled sensitive quantification of tabun adducts on human serum albumin by GC–MS/MS via isotope dilution
Organophosphorus nerve agents inhibit the cholinesterase activity by phosphylation of the active site serine. The resulting phosphylated cholinesterase and adducts on human serum albumin (HSA) are appropriate biomarkers for nerve agents exposure. Several methods have been developed for the detection...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Newlands Press Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923783/ https://www.ncbi.nlm.nih.gov/pubmed/31729243 http://dx.doi.org/10.4155/bio-2019-0161 |