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Overview of the relevance of PI3K pathway in HR-positive breast cancer

One of the hallmarks of hormone receptor (HR)-positive breast cancer is its dependence on the phosphatidylinositol-3-kinase (PI3K) pathway. Here, we review the epidemiologic, functional, and pharmacologic interactions between oncogenic PI3K and the estrogen receptor (ER). We discuss the epidemiology...

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Detalles Bibliográficos
Autores principales: Vasan, N, Toska, E, Scaltriti, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923788/
https://www.ncbi.nlm.nih.gov/pubmed/31859348
http://dx.doi.org/10.1093/annonc/mdz281