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Erastin/sorafenib induces cisplatin-resistant non-small cell lung cancer cell ferroptosis through inhibition of the Nrf2/xCT pathway

Non-small cell lung cancer (NSCLC) has long been one of the most lethal types of cancer due to its lack of typical clinical symptoms at early stages and high risk of tumour recurrence, even following complete surgical resection. Multicourse chemotherapy based on cisplatin (CDDP) is the standard adju...

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Detalles Bibliográficos
Autores principales: Li, Yu, Yan, Hengyi, Xu, Xiaoman, Liu, Hongbo, Wu, Cen, Zhao, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923844/
https://www.ncbi.nlm.nih.gov/pubmed/31897145
http://dx.doi.org/10.3892/ol.2019.11066