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DUF3669, a “domain of unknown function” within ZNF746 and ZNF777, oligomerizes and contributes to transcriptional repression

BACKGROUND: ZNF746 and ZNF777 belong to a subset of the large Krüppel-associated box (KRAB) zinc finger (ZNF) transcription factor family. They contain, like four other members in human, an additional conserved domain, the “domain of unknown function 3669” (DUF3669). Previous work on members of this...

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Detalles Bibliográficos
Autores principales: Al Chiblak, Mohannad, Steinbeck, Felix, Thiesen, Hans-Jürgen, Lorenz, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923878/
https://www.ncbi.nlm.nih.gov/pubmed/31856708
http://dx.doi.org/10.1186/s12860-019-0243-y