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Challenges in proteogenomics: a comparison of analysis methods with the case study of the DREAM proteogenomics sub-challenge

BACKGROUND: Proteomic measurements, which closely reflect phenotypes, provide insights into gene expression regulations and mechanisms underlying altered phenotypes. Further, integration of data on proteome and transcriptome levels can validate gene signatures associated with a phenotype. However, p...

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Detalles Bibliográficos
Autores principales: Eicher, Tara, Patt, Andrew, Kautto, Esko, Machiraju, Raghu, Mathé, Ewy, Zhang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923881/
https://www.ncbi.nlm.nih.gov/pubmed/31861998
http://dx.doi.org/10.1186/s12859-019-3253-z