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A hybrid and scalable error correction algorithm for indel and substitution errors of long reads
BACKGROUND: Long-read sequencing has shown the promises to overcome the short length limitations of second-generation sequencing by providing more complete assembly. However, the computation of the long sequencing reads is challenged by their higher error rates (e.g., 13% vs. 1%) and higher cost ($0...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923905/ https://www.ncbi.nlm.nih.gov/pubmed/31856721 http://dx.doi.org/10.1186/s12864-019-6286-9 |