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A hybrid and scalable error correction algorithm for indel and substitution errors of long reads

BACKGROUND: Long-read sequencing has shown the promises to overcome the short length limitations of second-generation sequencing by providing more complete assembly. However, the computation of the long sequencing reads is challenged by their higher error rates (e.g., 13% vs. 1%) and higher cost ($0...

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Detalles Bibliográficos
Autores principales: Das, Arghya Kusum, Goswami, Sayan, Lee, Kisung, Park, Seung-Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923905/
https://www.ncbi.nlm.nih.gov/pubmed/31856721
http://dx.doi.org/10.1186/s12864-019-6286-9