Synergistic effects of APOE and sex on the gut microbiome of young EFAD transgenic mice

BACKGROUND: Alzheimer’s disease (AD) is a fatal neurodegenerative disease. APOE4 is the greatest genetic risk factor for AD, increasing risk up to 15-fold compared to the common APOE3. Importantly, female (♀) APOE4 carriers have a greater risk for developing AD and an increased rate of cognitive dec...

Descripción completa

Detalles Bibliográficos
Autores principales: Maldonado Weng, Juan, Parikh, Ishita, Naqib, Ankur, York, Jason, Green, Stefan J., Estus, Steven, LaDu, Mary Jo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923910/
https://www.ncbi.nlm.nih.gov/pubmed/31861986
http://dx.doi.org/10.1186/s13024-019-0352-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923910/
https://www.ncbi.nlm.nih.gov/pubmed/31861986
http://dx.doi.org/10.1186/s13024-019-0352-2

Ejemplares similares