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Improved cell composition deconvolution method of bulk gene expression profiles to quantify subsets of immune cells
BACKGROUND: To facilitate the investigation of the pathogenic roles played by various immune cells in complex tissues such as tumors, a few computational methods for deconvoluting bulk gene expression profiles to predict cell composition have been created. However, available methods were usually dev...
Autores principales: | Chiu, Yen-Jung, Hsieh, Yi-Hsuan, Huang, Yen-Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923925/ https://www.ncbi.nlm.nih.gov/pubmed/31856824 http://dx.doi.org/10.1186/s12920-019-0613-5 |
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