MYCN and PRC1 cooperatively repress docosahexaenoic acid synthesis in neuroblastoma via ELOVL2

BACKGROUND: The MYCN amplification is a defining hallmark of high-risk neuroblastoma. Due to irregular oncogenes orchestration, tumor cells exhibit distinct fatty acid metabolic features from non-tumor cells. However, the function of MYCN in neuroblastoma fatty acid metabolism reprogramming remains...

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Detalles Bibliográficos
Autores principales: Ding, Yi, Yang, Jie, Ma, Yawen, Yao, Tengteng, Chen, Xingyu, Ge, Shengfang, Wang, Lihua, Fan, Xianqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923955/
https://www.ncbi.nlm.nih.gov/pubmed/31856871
http://dx.doi.org/10.1186/s13046-019-1492-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923955/
https://www.ncbi.nlm.nih.gov/pubmed/31856871
http://dx.doi.org/10.1186/s13046-019-1492-5

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