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Association between ALS and retroviruses: evidence from bioinformatics analysis

BACKGROUND: Emerging evidence suggests retroviruses play a role in the pathophysiology of amyotrophic lateral sclerosis (ALS). Specifically, activation of ancient viral genes embedded in the human genome is theorized to lead to motor neuron degeneration. We explore whether connections exist between...

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Detalles Bibliográficos
Autores principales: Klein, Jon P., Sun, Zhifu, Staff, Nathan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923964/
https://www.ncbi.nlm.nih.gov/pubmed/31861978
http://dx.doi.org/10.1186/s12859-019-3249-8