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Altered HDL particle in sickle cell disease: decreased cholesterol content is associated with hemolysis, whereas decreased Apolipoprotein A1 is linked to inflammation

BACKGROUND: Hypocholesterolemia is the most frequently encountered lipid abnormality in sickle cell disease (SCD). We enrolled pediatric patients to determine the relationships between lipid profile and parameters of hemolysis, oxidative stress and chronic inflammation in SCD. METHODS: The study inv...

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Detalles Bibliográficos
Autores principales: Yalcinkaya, Ahmet, Unal, Selma, Oztas, Yesim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924024/
https://www.ncbi.nlm.nih.gov/pubmed/31861992
http://dx.doi.org/10.1186/s12944-019-1174-5