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Interleukin-15 in cancer immunotherapy: IL-15 receptor complex versus soluble IL-15 in a cancer cell-delivered murine leukemia model

Cytokines of the common γ-chain receptor family such as IL-15 are vital with respect to activating immune cells, sustaining healthy immune functions, and augmenting the anti-tumor activity of effector cells, making them ideal candidates for cancer immunotherapy. IL-15, either in its soluble form (IL...

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Detalles Bibliográficos
Autores principales: Berger, Alexandra, Colpitts, Sarah J., Seabrook, Melanie S. S., Furlonger, Caren L., Bendix, Maura B., Moreau, Joshua M., McKillop, William M., Medin, Jeffrey A., Paige, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924073/
https://www.ncbi.nlm.nih.gov/pubmed/31856922
http://dx.doi.org/10.1186/s40425-019-0777-8