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Phosphocyclocreatine is the dominant form of cyclocreatine in control and creatine transporter deficiency patient fibroblasts

Creatine transporter deficiency (CTD) is a metabolic disorder resulting in cognitive, motor, and behavioral deficits. Cyclocreatine (cCr), a creatine analog, has been explored as a therapeutic strategy for the treatment of CTD. We developed a rapid, selective, and accurate HILIC ultra‐performance li...

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Detalles Bibliográficos
Autores principales: Gorshkov, Kirill, Wang, Amy Q., Sun, Wei, Fisher, Ethan, Frigeni, Marta, Singleton, Marc, Thorne, Natasha, Class, Bradley, Huang, Wenwei, Longo, Nicola, Do, Minh‐Ha T., Ottinger, Elizabeth A., Xu, Xin, Zheng, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924099/
https://www.ncbi.nlm.nih.gov/pubmed/31859463
http://dx.doi.org/10.1002/prp2.525