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Poly (ADP-ribosylation) of HMGB1 facilitates its acetylation and promotes HMGB1 translocation-associated chemotherapy-induced autophagy in leukaemia cells

Acute lymphoblastic leukaemia (ALL) is one of the most common and curable types of cancer in paediatric patients. However, chemotherapeutic resistance is a difficult but common obstacle when treating leukaemia in the clinical setting. Studies have demonstrated that drug resistance is partly attribut...

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Detalles Bibliográficos
Autores principales: Li, Yunyao, Xie, Jianwei, Li, Xinyu, Fang, Jianpei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924101/
https://www.ncbi.nlm.nih.gov/pubmed/31897149
http://dx.doi.org/10.3892/ol.2019.11116