Prediction of novel mouse TLR9 agonists using a random forest approach

BACKGROUND: Toll-like receptor 9 is a key innate immune receptor involved in detecting infectious diseases and cancer. TLR9 activates the innate immune system following the recognition of single-stranded DNA oligonucleotides (ODN) containing unmethylated cytosine-guanine (CpG) motifs. Due to the con...

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Detalles Bibliográficos
Autores principales: Khanna, Varun, Li, Lei, Fung, Johnson, Ranganathan, Shoba, Petrovsky, Nikolai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924143/
https://www.ncbi.nlm.nih.gov/pubmed/31856726
http://dx.doi.org/10.1186/s12860-019-0241-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924143/
https://www.ncbi.nlm.nih.gov/pubmed/31856726
http://dx.doi.org/10.1186/s12860-019-0241-0

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