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Few SINEs of life: Alu elements have little evidence for biological relevance despite elevated translation

Transposable elements colonize genomes and with time may end up being incorporated into functional regions. SINE Alu elements, which appeared in the primate lineage, are ubiquitous in the human genome and more than a thousand overlap annotated coding exons. Although almost all Alu-derived coding exo...

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Detalles Bibliográficos
Autores principales: Martinez-Gomez, Laura, Abascal, Federico, Jungreis, Irwin, Pozo, Fernando, Kellis, Manolis, Mudge, Jonathan M, Tress, Michael L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924539/
https://www.ncbi.nlm.nih.gov/pubmed/31886458
http://dx.doi.org/10.1093/nargab/lqz023