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Application of pharmacogenomics and bioinformatics to exemplify the utility of human ex vivo organoculture models in the field of precision medicine

Here we describe a collaboration between industry, the National Health Service (NHS) and academia that sought to demonstrate how early understanding of both pharmacology and genomics can improve strategies for the development of precision medicines. Diseased tissue ethically acquired from patients s...

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Detalles Bibliográficos
Autores principales: Cowan, Karen, Macluskie, Graeme, Finch, Michael, Palmer, Colin N. A., Hair, Jane, Bylesjo, Max, Lynagh, Sarah, Brankin, Pamela, McNeil, Marian, Low, Carolyn, Mallinson, David, Gourlay, Elaine M., Child, Hannah, Cheyne, Linda, Bunton, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924641/
https://www.ncbi.nlm.nih.gov/pubmed/31860681
http://dx.doi.org/10.1371/journal.pone.0226564