Deep sequence analysis of HIV adaptation following vertical transmission reveals the impact of immune pressure on the evolution of HIV

Human immunodeficiency virus (HIV) can adapt to an individual’s T cell immune response via genomic mutations that affect antigen recognition and impact disease outcome. These viral adaptations are specific to the host’s human leucocyte antigen (HLA) alleles, as these molecules determine which peptid...

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Detalles Bibliográficos
Autores principales: Currenti, Jennifer, Chopra, Abha, John, Mina, Leary, Shay, McKinnon, Elizabeth, Alves, Eric, Pilkinton, Mark, Smith, Rita, Barnett, Louise, McDonnell, Wyatt J., Lucas, Michaela, Noel, Francine, Mallal, Simon, Conrad, Joseph A., Kalams, Spyros A., Gaudieri, Silvana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924686/
https://www.ncbi.nlm.nih.gov/pubmed/31821379
http://dx.doi.org/10.1371/journal.ppat.1008177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924686/
https://www.ncbi.nlm.nih.gov/pubmed/31821379
http://dx.doi.org/10.1371/journal.ppat.1008177

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