Cargando…

Multi-omics profiling of mouse gastrulation at single cell resolution

Formation of the three primary germ layers during gastrulation is an essential step in the establishment of the vertebrate body plan and is associated with major transcriptional changes(1–5). Global epigenetic reprogramming accompanies these changes(6–8), but the role of the epigenome in regulating...

Descripción completa

Detalles Bibliográficos
Autores principales: Argelaguet, Ricard, Clark, Stephen J, Mohammed, Hisham, Stapel, L Carine, Krueger, Christel, Kapourani, Chantriolnt-Andreas, Imaz-Rosshandler, Ivan, Lohoff, Tim, Xiang, Yunlong, Hanna, Courtney W, Smallwood, Sebastien, Ibarra-Soria, Ximena, Buettner, Florian, Sanguinetti, Guido, Xie, Wei, Krueger, Felix, Göttgens, Berthold, Rugg-Gunn, Peter J., Kelsey, Gavin, Dean, Wendy, Nichols, Jennifer, Stegle, Oliver, Marioni, John C, Reik, Wolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924995/
https://www.ncbi.nlm.nih.gov/pubmed/31827285
http://dx.doi.org/10.1038/s41586-019-1825-8