EGFR806-CAR T cells selectively target a tumor-restricted EGFR epitope in glioblastoma

Targeting solid tumor antigens with chimeric antigen receptor (CAR) T cell therapy requires tumor specificity and tolerance toward variability in antigen expression levels. Given the relative paucity of unique cell surface proteins on tumor cells for CAR targeting, we have focused on identifying tum...

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Detalles Bibliográficos
Autores principales: Ravanpay, Ali C., Gust, Juliane, Johnson, Adam J., Rolczynski, Lisa S., Cecchini, Michelle, Chang, Cindy A., Hoglund, Virginia J., Mukherjee, Rithun, Vitanza, Nicholas A., Orentas, Rimas J., Jensen, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925027/
https://www.ncbi.nlm.nih.gov/pubmed/31903167
http://dx.doi.org/10.18632/oncotarget.27389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925027/
https://www.ncbi.nlm.nih.gov/pubmed/31903167
http://dx.doi.org/10.18632/oncotarget.27389

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