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Histopathological changes of acetaminophen-induced liver injury and subsequent liver regeneration in BALB/C and ICR mice

BACKGROUND AND AIM: Laboratory mice are widely used as a research model to provide insights into toxicological studies of various xenobiotic. Acetaminophen (APAP) is an antipyretic and analgesic drug that is commonly known as paracetamol, an ideal hepatotoxicant to exhibit centrilobular necrosis in...

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Detalles Bibliográficos
Autores principales: Muhammad-Azam, Fazil, Nur-Fazila, Saulol Hamid, Ain-Fatin, Raslan, Mustapha Noordin, Mohamed, Yimer, Nurhusien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Veterinary World 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925052/
https://www.ncbi.nlm.nih.gov/pubmed/32009746
http://dx.doi.org/10.14202/vetworld.2019.1682-1688