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Mutational change of CTX‐M‐15 to CTX‐M‐127 resulting in mecillinam resistant Escherichia coli during pivmecillinam treatment of a patient

Pivmecillinam (amdinocillin pivoxil) is the recommended first‐choice antibiotic used to treat urinary tract infections (UTIs) in Denmark. The frequency of mutation to mecillinam (MEC) resistance is described as high in vitro; however, treatment of UTI has a good clinical response and prevalence of m...

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Detalles Bibliográficos
Autores principales: Nielsen, Karen Leth, Hansen, Katrine Hartung, Nielsen, Jesper Boye, Knudsen, Jenny Dahl, Schønning, Kristian, Frimodt‐Møller, Niels, Hertz, Frederik Boëtius, Jansåker, Filip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925186/
https://www.ncbi.nlm.nih.gov/pubmed/31573735
http://dx.doi.org/10.1002/mbo3.941